The potential use of Reactive Oxygen gel in surgical prophylaxis

  • Matthew Dryden
    Matthew Dryden MD FRCPath FRCPS Department of Infection and Microbiology, Hampshire Hospitals Foundation NHS Trust and Southampton University Medical School, Southampton, UK. Conflicts of interest: none declared
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Published:October 25, 2021DOI:


      The principles of antibiotic use in surgical prophylaxis remain the same. The purpose of this review is to introduce the investigational agent Reactive Oxygen as a possible surgical prophylaxis agent, particularly in the light of the global crisis in antibiotic resistance. There is evidence for its efficacy in the treatment of infected soft tissue and early clinical data for its efficacy in reducing infection in clean surgery (caesarean section), and in complex contaminated surgery (abdominal wall repair and prosthetic joint salvage).


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