Surgery
Volume 20, Issue 8 , Pages 177-179, 1 August 2002

Rational Antibiotic Therapy

Andrew J H Simpson is Consultant in Medical Microbiology at the Royal Free Hospital, London, UK. He qualified from King's College Hospital and trained in microbiology at St Bartholomew's Hospital, London, UK. His research interests include melioidosis and the control of antibiotics in hospitals

Abstract 

‘Successful chemotherapy must be rational, and rational treatment demands a diagnosis. This may only be provisional, and it may later be proved wrong, but the treatment chosen should be based on some explicit assumption as to the nature of the disease process.’ This passage, from the second edition of ‘Antibiotic and Chemotherapy’ by Garrod and O'Grady, published in 1968, may be applied to all forms of drug treatment, and to antimicrobial therapy in particular.

Keywords:  infection , rational , antibiotic , therapy

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PII: S0263-9319(06)70251-4

doi:10.1383/surg.20.8.177.14524

Surgery
Volume 20, Issue 8 , Pages 177-179, 1 August 2002

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